Suggest both of those people and caregivers regarding the threats of respiratory melancholy and sedation when OXYCONTIN is used with benzodiazepines or other CNS depressants (including Liquor and illicit prescription drugs). Recommend sufferers to not travel or operate hefty machinery until finally the effects of concomitant use in the benzodiazepine or other CNS depressant are actually established.
Advise people in the likely for significant constipation, which include administration instructions and when to hunt health care interest [see ADVERSE REACTIONS and CLINICAL PHARMACOLOGY].
The oxycodone in OXYCONTIN may bring about spasm of your sphincter of Oddi. Opioids may perhaps bring about increases during the serum amylase. Often Assess people with biliary tract disorder, such as acute pancreatitis, for worsening symptoms.
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If concomitant use is essential, look at dosage reduction of OXYCONTIN until stable drug effects are realized. Evaluate clients at Regular intervals for respiratory melancholy and sedation.
The dosage is predicated on your own clinical issue and response to procedure. Do not increase your dose, go ahead and take medication extra normally, or choose it for a longer time than prescribed. Effectively prevent the medication when so directed.
Thanks to related pharmacological Homes, it really is acceptable to be expecting related hazard with the concomitant usage of other CNS depressant prescription drugs with opioid analgesics [see DRUG INTERACTIONS].
Hence, if urine tests for oxycodone is taken into account in the clinical management of an individual affected individual, make sure the sensitivity and specificity on the assay is appropriate, and take into account the restrictions from the testing used when interpreting outcomes.
Extended usage of OXYCONTIN through pregnancy can lead more info to neonatal opioid withdrawal syndrome, which may be lifetime-threatening Otherwise regarded and addressed, and needs management In keeping with protocols produced by neonatology specialists.
The dosage is based on your health-related ailment and response to treatment method. Don't improve your dose, go ahead and take medication extra typically, or consider it for an extended time than prescribed. Correctly end the medication when so directed.
The existence of possibility variables for overdose mustn't stop the appropriate administration of soreness in any offered affected person [see WARNINGS AND PRECAUTIONS].
Store at place temperature far from gentle and moisture. Never keep in the toilet. Maintain all prescription drugs faraway from youngsters and pets. See also Warning part.
Notice this record is just not all-inclusive and features only widespread drugs that will communicate with OxyContin. You must make reference to the prescribing info for OxyContin for a whole list of interactions.
Abuse of and dependancy to opioids in certain people today might not be website accompanied by check here concurrent tolerance and signs and symptoms of Actual physical dependence. Moreover, abuse of opioids can take place within the absence of dependancy.